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Updated: Apr 20, 2026

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer
Published on: February 27, 2026
Video-assisted thoracoscopic (VATS) lobectomy after induction therapy
Nathan M Mollberg1, Michael S Mulligan1
1Division of Cardiothoracic Surgery, Department of Surgery, University of Washington, Seattle, WA 98195, USA.
Video-assisted thoracoscopic lobectomy (VATS) is now safely applicable to patients after neoadjuvant therapy. This approach offers a less invasive option, potentially improving outcomes for compromised patients undergoing pulmonary resection.
Area of Science:
- Thoracic Surgery
- Oncology
- Pulmonary Medicine
Background:
- Neoadjuvant chemotherapy and chemoradiotherapy can affect the pleural space, previously limiting minimally invasive lung cancer surgery.
- Video-assisted thoracoscopic surgery (VATS) has advanced, enabling more complex procedures.
- VATS may offer better pulmonary function preservation compared to traditional open surgery.
Purpose of the Study:
- To describe a safe approach for performing VATS lobectomy in patients who have received neoadjuvant therapy.
- To evaluate the feasibility and safety of VATS lobectomy in a carefully selected patient cohort post-induction therapy.
Main Methods:
- Description of a specific surgical technique for VATS lobectomy tailored for patients with prior neoadjuvant treatment.
- Careful patient selection criteria emphasizing safety and suitability for VATS.
Main Results:
- The described VATS approach was designed for maximal safety in selected patients.
- Increased experience with VATS has expanded its application to more demanding surgeries.
Conclusions:
- VATS lobectomy can be safely performed in patients following neoadjuvant therapy.
- The VATS approach may be particularly beneficial for compromised patients due to its diminished impact on pulmonary function.
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