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[Maxillary tumor revealing primary hyperparathyroidism].
M Abou-Elfadl1, A Belamkaddem1, M Mahtar1
1Service d'ORL et de chirurgie cervico-faciale, hôpital 20-Août, CHU Ibn Rochd, Casablanca, Maroc.
Summary
Giant cell tumors of the jaw can rarely indicate primary hyperparathyroidism. Surgical removal of the jaw mass and parathyroid adenoma resolved the condition in a 70-year-old male patient.
Area of Science:
- Endocrinology
- Oral Surgery
- Oncology
Background:
- Primary hyperparathyroidism infrequently manifests as a giant cell tumor (GCT) of the jaw.
- This case highlights a GCT as the initial presentation leading to the diagnosis of a parathyroid adenoma.
Observation:
- A 70-year-old male presented with a swollen jaw and osteolytic lesions in the maxilla.
- Biochemical analysis revealed hypercalcemia, hypophosphatemia, and elevated parathyroid hormone (PTH) levels.
- Neck ultrasonography identified a parathyroid adenoma.
Findings:
- Surgical excision of both the maxillary GCT and the parathyroid adenoma was performed.
- Post-operative normalization of calcium and phosphate levels confirmed successful treatment.
- Maxillary GCTs are an exceptionally rare presentation of primary hyperparathyroidism.
Implications:
- This case underscores the importance of considering endocrine disorders in patients with seemingly isolated jaw tumors.
- Elevated PTH levels and characteristic imaging are crucial for diagnosing underlying hyperparathyroidism.
- Surgical intervention is the definitive treatment for both the GCT and the parathyroid adenoma.
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