Related Experiment Video
Updated: Apr 20, 2026

Generation of High-Throughput Three-Dimensional Tumor Spheroids for Drug Screening
Published on: September 5, 2018
A new application of value-stream mapping in new drug development: a case study within Novartis
Mareike Heinzen1, Samuel Mettler2, Annina Coradi1
1ETH Zürich, Scheuchzerstrasse 7, 8092 Zürich, Switzerland.
Abstract:
In this case study, we evaluated the effect of colocation on the drug development process using value-stream mapping (VSM) on the Novartis Campus in Basel, Switzerland. We compared a colocated team with a control group that was not colocated. The data showed that colocation was not associated with increased process speed in terms of lead lines. However, the colocated team communicated more and reported beneficial experiences, such as faster working processes or improved mutual understanding. VSM workshops revealed not only performance indicators about colocation, but also enhanced communication and cooperation through the evolving discussion.

