Related Experiment Video
Updated: Apr 20, 2026

Asthma Detection Research Based on Voice Signal Processing and Machine Learning
Published on: July 22, 2025
[Exercise-induced vocal cord dysfunction in asthma: a new diagnostic method].
Jérémie Taverne1, Philippe Ramon2, Clément Fournier2
1Université de Lille 2, hôpital Calmette, clinique des maladies respiratoires, service de pneumologie et immuno-allergologie, 59037 Lille cedex, France.
Vocal cord dysfunction (VCD) can mimic asthma. A new method measuring vocal cord opening angle (VCOA) during exercise identified exercise-induced VCD (IEVCD) in 26% of uncontrolled asthma patients.
Area of Science:
- Pulmonology
- Otolaryngology
Context:
- Vocal cord dysfunction (VCD) is a challenging diagnosis, often presenting with symptoms similar to asthma.
- Exercise-induced VCD (IEVCD) can coexist with asthma, complicating diagnosis and management.
- Unexplained exertional dyspnea in asthmatics warrants investigation for concurrent IEVCD.
Purpose:
- To evaluate a novel, straightforward method for diagnosing IEVCD by analyzing vocal cord behavior.
- To determine the prevalence of IEVCD in a cohort of asthma patients with persistent, unexplained exertional dyspnea.
Summary:
- A prospective study utilized cardiopulmonary exercise testing and laryngoscopy to measure the vocal cord-opening angle (VCOA) during exercise.
- Lower inspiratory VCOA values were observed in asthmatic patients compared to controls.
- 26% of the 15 participating uncontrolled asthma patients were diagnosed with IEVCD, defined by an inspiratory VCOA peak <49°.
Impact:
- Measurement of VCOA provides objective data for diagnosing VCD, a previously under-recognized condition.
- IEVCD is prevalent in uncontrolled asthma and may be an under-diagnosed factor exacerbating asthma symptoms.
- Accurate diagnosis and management of IEVCD can potentially simplify asthma treatment regimens.
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