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Humanized NOG Mice for Intravaginal HIV Exposure and Treatment of HIV Infection
Published on: January 31, 2020
Contemporary management of human immunodeficiency virus in pregnancy
Meghan Donnelly1, Jill K Davies2
1Department of Obstetrics and Gynecology, University of Colorado Health, University of Colorado Denver School of Medicine, 12631 East 17th Avenue, Aurora, CO 80045, USA.
Abstract:
Contemporary management of HIV in pregnancy remains a moving target. With the development of newer antiretroviral agents with lower side-effect profiles and laboratory methods for detection and monitoring of HIV, considerable progress has been made. This review examines key concepts in the pathophysiology of HIV and pregnancy with emphasis on perinatal transmission and reviews appropriate screening and diagnostic testing for HIV during pregnancy. Current recommendations for medical, pharmacologic, and obstetric management of women newly diagnosed with HIV during pregnancy and for those women with preexisting infection are discussed. Preconception counseling for HIV+ women as well as postpartum issues are addressed.
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