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Prevention and management of viral hepatitis in pregnancy

Martha W F Rac1, Jeanne S Sheffield1

  • 1Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9032, USA.

Obstetrics and Gynecology Clinics of North America
|December 3, 2014
PubMed

Insights

Viral hepatitis during pregnancy, especially HBV and HCV, poses risks to mothers and infants. Early detection and management of all five viral hepatitis types are crucial for optimizing outcomes and preventing transmission.

Area of Science:

  • Hepatology
  • Infectious Diseases
  • Maternal-Fetal Medicine

Background:

  • Hepatitis B virus (HBV) and Hepatitis C virus (HCV) are leading causes of chronic liver disease, cirrhosis, and liver cancer.
  • Pregnancy with viral hepatitis can lead to adverse maternal and fetal outcomes.
  • Early identification of viral hepatitis in pregnancy is vital for timely intervention.

Purpose of the Study:

  • To review the prevention and management strategies for all five viral hepatitis syndromes (HAV-HEV) during pregnancy.
  • To highlight the significance of early diagnosis in optimizing pregnancy outcomes.
  • To discuss methods for minimizing perinatal transmission of viral hepatitis.

Main Methods:

  • Literature review of current guidelines and research on viral hepatitis in pregnancy.
  • Synthesis of information on prevention, diagnosis, and management protocols.
  • Analysis of the impact of viral hepatitis on maternal and fetal health.

Main Results:

  • HBV and HCV are the most prevalent causes of chronic hepatitis, contributing significantly to cirrhosis and liver cancer.
  • Viral hepatitis infection during pregnancy can negatively affect both mother and fetus.
  • Prompt identification enables effective management to improve pregnancy outcomes and reduce transmission.

Conclusions:

  • Comprehensive management of all viral hepatitis types during pregnancy is essential.
  • Early detection and intervention are key to mitigating risks associated with viral hepatitis in pregnancy.
  • Effective strategies can optimize maternal and infant health and prevent perinatal transmission.

Keywords:
Hepatitis AHepatitis BHepatitis CHepatitis DHepatitis EPregnancyViral hepatitis

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