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Ex Vivo Infection of Murine Epidermis with Herpes Simplex Virus Type 1
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Ex Vivo Infection of Murine Epidermis with Herpes Simplex Virus Type 1

Published on: August 24, 2015

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Herpes simplex virus infection during pregnancy

Alyssa Stephenson-Famy1, Carolyn Gardella2

  • 1Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Washington, Box 356460, Seattle, WA 98195, USA.

Obstetrics and Gynecology Clinics of North America
|December 3, 2014
PubMed

Genital herpes in pregnancy continues to cause significant maternal morbidity, with an increasing number of infections being due to oral-labial transmission of herpes simplex virus (HSV)-1. Near delivery, primary infections with HSV-1 or HSV-2 carry the highest risk of neonatal herpes infection, which is a rare but potentially devastating disease for otherwise healthy newborns. Prevention efforts have been limited by lack of an effective intervention for preventing primary infections and the unclear role of routine serologic testing.

Keywords:
Antiviral therapyGenital herpesNeonatal herpesPregnancyPreventionSerologic screening

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