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Biological Compatibility Profile on Biomaterials for Bone Regeneration
Published on: November 16, 2018
Extraction site preservation using an in-situ hardening alloplastic bone graft substitute
Minas D Leventis1, Peter Fairbairn2, Robert A Horowitz3
1Researcher, Department of Oral and Maxillofacial Surgery, Dental School, University of Athens, Greece, Private Practice, Oral Surgery and Implant Dentistry, Athens, Greece.
Abstract:
This case report highlights the use of an in-situ hardening alloplastic bone grafting material composed of beta-tricalcium phosphate (β-TCP) granules coated with poly(lactic-co-glycolic acid) (PLGA) to preserve the dimensions and architecture of the alveolar ridge after atraumatic extraction. This material provided a stable scaffold that, although left uncovered, deterred the ingrowth of unwanted soft tissue, allowing newly formed keratinized soft tissue to proliferate over the healing grafted socket and gradually cover the site. At re-entry after 4 months adequate newly formed bone was observed, allowing for the correct positional placement of an implant. The results of this case suggest that an in-situ hardening alloplastic grafting material can be successfully utilized with minimally invasive procedures to preserve the bone and the soft-tissue profile of the alveolar ridge for future implant rehabilitation.

