Presentation of pulmonary Langerhans cell histiocytosis before the development of lung cysts
Related Experiment Video For Interstitial lung disease
Updated: Apr 20, 2026
Multidimensional Coculture System to Model Lung Squamous Carcinoma Progression
Published on: March 17, 2020
Irene Martin1, Marta Ballester2, Yolanda Ruiz3
1Interstitial Lung Disease Unit, Hospital Universitari de Bellvitge L'Hospitalet de Llobregat, Barcelona, Spain.
Abstract:
Pulmonary Langerhans cell histiocytosis (PLCH) affects mainly young, predominantly smoking adults with a peak at 20-40 years of age. Patients with PLCH often present with a nonproductive cough and/or dyspnea. High-resolution CT (HRCT) is the most important diagnostic modality in PLCH. The typical HRCT pattern combines small poorly limited nodules, cavitated nodules, and finally thick- and thin-walled cysts. In rare cases, HRCT enables PLCH to be diagnosed prior to the development of cysts.
