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Clozapine-induced rabbit syndrome: a case report
1Department of Psychiatry, Faculty of Medicine, Rize University , Rize, Turkey.
Mental Illness
|December 6, 2014
Summary
Rabbit syndrome (RS) involves rhythmic mouth movements caused by antipsychotics. This case highlights the risk of RS with clozapine, an atypical antipsychotic, in a patient with schizophrenia.
Area of Science:
- Neurology
- Psychiatry
- Pharmacology
Background:
- Rabbit syndrome (RS) is an antipsychotic-induced movement disorder.
- Typically associated with older typical antipsychotics.
- Risk with newer atypical antipsychotics is less understood.
Observation:
- A 44-year-old female patient with paranoid schizophrenia for 22 years.
- Developed RS during a 10-month treatment with clozapine.
- Characterized by vertical mouth/lip movements at 5 Hz, without tongue involvement.
Findings:
- This case adds to isolated reports of RS with atypical antipsychotics.
- Suggests clozapine may pose a risk for developing RS.
- Further research is needed to quantify the risk of RS with atypical agents.
Implications:
- Clinicians should be aware of the potential for RS with clozapine.
- Monitoring for movement disorders is crucial in patients on atypical antipsychotics.
- Understanding atypical antipsychotic-induced movement disorders informs safer prescribing practices.
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