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Preparation of Naringenin Solution for In Vivo Application
Published on: August 10, 2021
Nardosinane-type sesquiterpenoids of Nardostachys chinensis Batal
Jin-Bo Zhang1, Ming-Li Liu1, Chang Li2
1Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, PR China.
Abstract:
Four new nardosinane-type sesquiterpenoids nardosinanones F-I (1-2, 4-5), along with eight known sesquiterpenoids (3, 6-12) were isolated from the underground parts of Nardostachys chinensis Batal. Their structures were elucidated on the basis of extensive spectroscopic analysis. Compounds 1 and 2 were new nardosinane sesquiterpenoids processing a rare 4,11-epoxy group in nature. In addition, compounds 1, 5-7, 11 and 12 showed protective effects on neonatal rat cardiomyocyte injury induced by hydrogen peroxide.

