Related Experiment Video
Updated: Aug 25, 2026

06:38
Establishment of Epstein-Barr Virus Growth-transformed Lymphoblastoid Cell Lines
Published on: November 8, 2011
The impact of EBV hybridization in clinical and biological medicine
1Service de Bactériologie-Virologie, Hôpital Saint-Louis, Université Paris VII, France.
Abstract:
Hybridization technology allows the detection of EBV (Epstein-Barr Virus) DNA in lymphoproliferative diseases in immunosuppressed patients. Moreover, in HIV infected patients, LIP (Lymphocytic Interstitial Pneumonitis), hairy leucoplasia and lymphoma are associated with EBV by DNA hybridization. These procedures are also useful for understanding interactions between EBV and epithelial cells.
Related Concept Videos
Hybridoma Technology
Hybridoma technology is used for the large-scale production of monoclonal antibodies. Monoclonal antibodies bind to only a single antigenic determinant or epitope. Such antibodies are used in research, diagnostics, and disease therapy. The hybridoma technology established in 1975 by Georges Köhler and Cesar Milstein was awarded the Nobel Prize in Medicine in 1984 for revolutionizing research and therapy.
Hybridoma Selection
Commonly used fusion techniques — electroporation, polyethylene glycol...
Hybridoma Selection
Commonly used fusion techniques — electroporation, polyethylene glycol...
Cytomegalovirus Disease
Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...

