Related Experiment Video
Updated: Apr 19, 2026

Facile and Efficient Preparation of Tri-component Fluorescent Glycopolymers via RAFT-controlled Polymerization
Published on: June 19, 2015
Advances in multifunctional glycosylated nanomaterials: preparation and applications in glycoscience
Avijit K Adak1, Ben-Yuan Li1, Chun-Cheng Lin1
1Department of Chemistry, National Tsing Hua University, Hsinchu 30013, Taiwan.
Abstract:
Applications of glycosylated nanomaterials have gained considerable attention in recent years due to their unique structural properties and compatibility in biological systems. In this review, glyco-nanoparticles (glyco-NPs) are defined as compounds that contain a nano-sized metallic core, are composed of noble metals, magnetic elements, or binary inorganic nanoparticles, and that exhibit carbohydrate ligands on the surface in three dimensional polyvalent displays similar to the glycocalyx structures on cell membranes. Nanomaterials decorated with suitable biological recognition ligands have yielded novel hybrid nanobiomaterials with synergistic functions, especially in biomedical applications. This review focuses on strategies for building various types of glyco-NPs and highlights their potential in targeted drug delivery and molecular imaging as well as their uses in bioassays and biosensors. The most recent examples of glyco-NPs as vaccine candidates and probes for assaying enzymes with bond-forming activities are also discussed.
Related Concept Videos
Protein Glycosylation
Glycosylation occurs in...
Glycocalyx and its Functions
Site-Targeted Drug Delivery Systems: Polymeric Carriers
Glycosaminoglycans
GAGS are found in the extracellular matrix of vertebrates, invertebrates, and bacteria. Due to their polar nature they attract water, and serve as excellent lubricants or shock absorbers in an animal body.
Hyaluronic...
Oligosaccharide Assembly
Multiple sugar molecules that may or may...

