Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Genetic Screens02:46

Genetic Screens

5.9K
Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...
5.9K
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

7.3K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
7.3K
Genetic Variation01:25

Genetic Variation

1.6K
Genetic variation is the diversity in DNA sequences found among individuals of the same species. This diversity is crucial for a species' survival because it helps organisms adapt to environmental changes. Genetic variation begins with fertilization, where an egg and sperm cell merge. Each of these cells carries 23 chromosomes, up to 46 in the fertilized egg. Chromosomes are long DNA strands that contain genes, the basic units of heredity.
Genes exist in different versions called alleles,...
1.6K
Mutation, Gene Flow, and Genetic Drift01:09

Mutation, Gene Flow, and Genetic Drift

66.5K
In a population that is not at Hardy-Weinberg equilibrium, the frequency of alleles changes over time. Therefore, any deviations from the five conditions of Hardy-Weinberg equilibrium can alter the genetic variation of a given population. Conditions that change the genetic variability of a population include mutations, natural selection, non-random mating, gene flow, and genetic drift (small population size).
66.5K
Genomics02:02

Genomics

42.0K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
42.0K
What is Population Genetics?01:25

What is Population Genetics?

66.3K
A population is composed of members of the same species that simultaneously live and interact in the same area. When individuals in a population breed, they pass down their genes to their offspring. Many of these genes are polymorphic, meaning that they occur in multiple variants. Such variations of a gene are referred to as alleles. The collective set of all the alleles within a population is known as the gene pool.
66.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sarcomatoid Renal Cell Carcinoma Has a Distinct Molecular Pathogenesis, Driver Mutation Profile, and Transcriptional Landscape.

Clinical cancer research : an official journal of the American Association for Cancer Research·2017
Same author

Cell type-selective imaging and profiling of newly synthesized proteomes by using puromycin analogues.

Chemical communications (Cambridge, England)·2017
Same author

A cheat sheet to navigate the complex maze of pharmaceutical exclusivities in Europe.

Pharmaceutical patent analyst·2017
Same author

Hydroxamic Acids as Chemoselective (ortho-Amino)arylation Reagents via Sigmatropic Rearrangement.

Angewandte Chemie (International ed. in English)·2017
Same author

Nerve Growth Factor Is Associated With Sexual Pain in Women With Endometriosis.

Reproductive sciences (Thousand Oaks, Calif.)·2017
Same author

C-Terminal Domain of Hemocyanin, a Major Antimicrobial Protein from <i>Litopenaeus vannamei</i>: Structural Homology with Immunoglobulins and Molecular Diversity.

Frontiers in immunology·2017

Related Experiment Video

Updated: Apr 19, 2026

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

2.9K

Genetic data simulators and their applications: an overview.

Bo Peng1, Huann-Sheng Chen, Leah E Mechanic

  • 1Department of Bioinformatics and Computational Biology, The University of Texas, MD Anderson Cancer Center, Houston, Texas, United States of America.

Genetic Epidemiology
|December 16, 2014
PubMed
Summary
This summary is machine-generated.

This study reviews 93 genetic simulators, detailing their development, features, and applications. The Genetic Simulation Resources (GSR) website aids researchers in selecting appropriate tools for complex genetic studies.

Keywords:
genetic simulationgenetic simulation resourcessoftware

More Related Videos

In Vivo Modeling of the Morbid Human Genome using Danio rerio
12:31

In Vivo Modeling of the Morbid Human Genome using Danio rerio

Published on: August 24, 2013

21.6K
Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
09:34

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Published on: April 4, 2018

35.1K

Related Experiment Videos

Last Updated: Apr 19, 2026

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

2.9K
In Vivo Modeling of the Morbid Human Genome using Danio rerio
12:31

In Vivo Modeling of the Morbid Human Genome using Danio rerio

Published on: August 24, 2013

21.6K
Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
09:34

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Published on: April 4, 2018

35.1K

Area of Science:

  • Computational Biology
  • Genetics
  • Bioinformatics

Background:

  • Computer simulations are crucial for developing statistical models in genetic studies.
  • Numerous simulation programs exist, varying in reliability and application scope.
  • A centralized resource is needed to compare and select genetic simulators.

Purpose of the Study:

  • To summarize the properties of 93 genetic simulators registered on the Genetic Simulation Resources (GSR) website.
  • To provide an overview of the development and applications of genetic simulation software.
  • To aid researchers in choosing appropriate simulation tools for their studies.

Main Methods:

  • Compilation and summarization of data from 93 registered genetic simulators on the GSR website.
  • Analysis of over 160 defined attributes for each simulator.
  • Review of cited publications to understand simulator applications and utilization.

Main Results:

  • The GSR website currently hosts 93 genetic simulators with detailed attribute information.
  • The study provides a historical perspective on the development and features of these simulators.
  • Analysis of publications reveals diverse applications and usage patterns of genetic simulations.

Conclusions:

  • The GSR website serves as a valuable resource for researchers in genetic studies.
  • Understanding simulator features and historical development aids in tool selection.
  • Genetic simulations are widely utilized across various disciplines for complex evolutionary and genetic analyses.