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Published on: February 23, 2017
Development of dielectric-barrier-discharge ionization
Cheng'an Guo1, Fei Tang, Jin Chen
1State Key Laboratory of Precision Measurement Technology and Instruments, Department of Precision Instrument, Tsinghua University, Beijing, 100084, China.
Dielectric-barrier-discharge ionization offers a versatile, low-energy, solvent-free method for ambient ionization. This review covers its instrumentation, applications in fields like biological analysis and forensics, and future potential.
Area of Science:
- Analytical Chemistry
- Physical Chemistry
- Mass Spectrometry
Background:
- Dielectric-barrier-discharge ionization is an ambient ionization technique introduced in 2007.
- It has gained significant attention due to its advantages such as low energy consumption, solvent-free operation, and ease of miniaturization.
Purpose of the Study:
- To provide a comprehensive review of dielectric-barrier-discharge ionization.
- To detail its instrumentation, applications, and mechanistic studies.
- To discuss potential future uses of this ionization source.
Main Methods:
- Review of existing literature on dielectric-barrier-discharge ionization.
- Summarization of instrumentation and mechanistic studies.
- Analysis of diverse applications across various scientific fields.
Main Results:
- Dielectric-barrier-discharge ionization is effective in biological analysis, food safety, mass-spectrometry imaging, forensic identification, and reaction monitoring.
- The technique's advantages make it suitable for a wide range of analytical challenges.
- Mechanistic insights and instrumentation advancements are crucial for its continued development.
Conclusions:
- Dielectric-barrier-discharge ionization is a promising ambient ionization technique with broad applicability.
- Further research into its mechanisms and instrumentation will expand its utility.
- The technique holds significant potential for future innovations in analytical science.
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