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Updated: Apr 19, 2026
Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
Published on: June 14, 2021
ESC-derived retinal pigmented epithelial cell transplants in patients: so far, so good
1Stem Cells and Regenerative Medicine Section, UCL Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, UK.
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Many untreatable blinding diseases involve degeneration of retinal pigmented epithelial (RPE) cells, which has prompted exploration of the therapeutic potential of human-pluripotent-stem-cell-derived RPE. The first safety trials reported in The Lancet of embryonic-stem-cell-derived RPE cell transplants indicate no serious adverse outcomes and encourage further investigation.
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