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Modeling Retinitis Pigmentosa with Patient-Derived iPSCs

Yeh Chwan Leong1, Jane C Sowden2

  • 1Stem Cells and Regenerative Medicine Section, UCL Great Ormond Street Institute of Child Health, University College London and NIHR Great Ormond Street Hospital Biomedical Research Centre, London, UK.

Advances in Experimental Medicine and Biology
|July 13, 2023
PubMed
Summary

Patient-derived induced pluripotent stem cells (iPSCs) offer a superior model for studying retinitis pigmentosa (RP) compared to animal models. This approach aids in understanding photoreceptor death and developing new therapies for retinal degeneration.

Keywords:
Disease mechanismsDisease modelingPhotoreceptorsRetina degenerativeRetinal organoidsRetinitis pigmentosaiPSC

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