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Updated: Apr 19, 2026

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Controlled Cortical Impact Model for Traumatic Brain Injury
Published on: August 5, 2014
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Moderate-to-severe traumatic brain injury
Paul Pasquina1, Robert Kirtley1, Geoffrey Ling2
1Departments of Physical Medicine and Rehabilitation, Uniformed Services University of the Health Sciences, Bethesda, Maryland.
Seminars in Neurology
|December 19, 2014
Summary
Caring for moderate-to-severe traumatic brain injury (TBI) patients, especially from combat blast injuries, requires an interdisciplinary team. Rehabilitation is key across all care stages to maximize recovery, independence, and quality of life.
Area of Science:
- Neuroscience
- Rehabilitation Medicine
- Trauma Surgery
Background:
- Managing moderate-to-severe traumatic brain injury (TBI), particularly combat-related blast injuries, presents significant clinical challenges.
- Optimal patient outcomes necessitate a coordinated, interdisciplinary team approach.
- A holistic care strategy is crucial throughout the entire continuum of care due to TBI's multifaceted manifestations.
Observation:
- This article outlines interdisciplinary care delivery from acute to chronic settings for TBI patients.
- Rehabilitation's pivotal role in maximizing recovery, functional independence, and quality of life is highlighted.
- A case presentation of blast-related polytrauma illustrates common TBI-associated conditions.
Findings:
- Interdisciplinary care models are essential for comprehensive TBI management.
- Rehabilitation interventions significantly impact functional recovery and patient-reported outcomes.
- Addressing neurointensive care, seizures, VTE prevention, spasticity, vestibular, endocrine, and psychological issues is vital.
Implications:
- Implementing integrated, interdisciplinary care pathways can improve TBI patient trajectories.
- Early and continuous rehabilitation is critical for optimizing long-term functional independence and quality of life post-TBI.
- Understanding and managing the diverse sequelae of TBI, including psychological trauma, is paramount for holistic patient recovery.

