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Gynecologic Malignancies Post-LeFort Colpocleisis
Rayan Elkattah1, Alicia Brooks2, R Keith Huffaker3
1Department of Obstetrics and Gynecology, Quillen College of Medicine, East Tennessee State University, 325 N State of Franklin Road, Johnson City, TN 37604, USA.
Case Reports in Obstetrics and Gynecology
|December 20, 2014
Summary
LeFort colpocleisis (LFC) is a treatment for advanced pelvic organ prolapse. Gynecologic cancers after LFC are rare, but a new evaluation strategy is proposed.
Area of Science:
- Gynecology
- Surgical Oncology
Background:
- LeFort colpocleisis (LFC) is a surgical option for advanced pelvic organ prolapse in older women.
- A significant limitation of LFC is the difficulty in diagnosing subsequent gynecologic malignancies.
Purpose of the Study:
- To report the first case of endometrioid ovarian cancer following LFC.
- To review all reported gynecologic malignancies diagnosed after LFC in the English medical literature.
- To propose a strategy for evaluating post-LFC malignancies.
Main Methods:
- Case report of endometrioid ovarian cancer after LFC.
- Systematic literature review of gynecologic malignancies post-LFC.
Main Results:
- The reported case is the second ovarian cancer and the first endometrioid subtype diagnosed after LFC.
- A total of nine other gynecologic malignancies have been previously reported post-LFC.
- Gynecologic malignancies are rare complications following LFC.
Conclusions:
- Gynecologic malignancies are infrequent after LeFort colpocleisis.
- A simple 3-step strategy is proposed for the evaluation of post-LFC malignancies.

