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Updated: Apr 19, 2026

Generation of Lymph Node-fat Pad Chimeras for the Study of Lymph Node Stromal Cell Origin
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Maturation of embryonic tissues in a lymph node: a new approach for bioengineering complex organs

Maria Giovanna Francipane1, Eric Lagasse

  • 1a McGowan Institute for Regenerative Medicine; Department of Pathology ; University of Pittsburgh School of Medicine ; Pittsburgh , PA USA.

Organogenesis
|December 23, 2014
PubMed

Keywords:
21wEcT, 21-week ectopic thymus2D, 2-dimensional3D, 3-dimensional3wEcI, 3-week ectopic intestine3wEcL, 3-week ectopic lung3wEcS, 3-week ectopic stomach6wEcT, 6-week ectopic thymusAdT, adult thymusAire, autoimmune regulatorCgA, chromogranin AE14.5/15.5, embryonic day 14.5 to 15.5ECM, extracellular matrixER-TR7, reticular fibroblasts and reticular fibersEmI, embryonic intestineEmL, embryonic lungEmS, embryonic stomachEmT, embryonic thymusEpCAM1, epithelial cell adhesion molecule 1FACS, fluorescence-activated cell sortingFAH, fumarylacetoacetate hydrolaseGFAPδ, glial fibrillary acid protein deltaGM-CSF, granulocyte-macrophage colony-stimulating factorK5, keratin 5K8, keratin 8LN, lymph nodeMAP-2, Microtubule-associated protein 2bioreactorcTEC, cortical thymic epithelial cellchimerismdevelopmentlymph nodemTEC, medullary thymic epithelial cellmTOR, mammalian target of rapamycinterminal differentiation

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