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[Determination of methyl propyl ketone in air of workplace by capillary gas chromatography]
Jian Zhang1, Wanchao Zhang1, Shulan Zhao1
1Tianjin Centers for Disease Control and Prevention, 6th Huayue Street, Tianjin 300011, China.
Objective:
To establish a gas chromatography method for determination of methyl propyl ketone in the air of workplace.
Methods:
Methyl propyl ketone in the air of workplace was collected with activated carbon tubes and desorbed with carbon disulfide before sample loading. The target toxicant was separated with the capillary column and detected with a hydrogen flame ionization detector, identified by retention time, and quantified by peak area.
Results:
The linear range of methyl propyl ketone in the air of workplace was 202.5∼4 860.0 µg/ml, with a correlation coefficient of 0.999 98. The limit of detection was 1.5 µg/ml. The lower limit of quantification was 5.0 µg/ml. The minimum detectable concentration was 1.0 mg/m(3) under 1.5 L sampling volume and 1.0 ml desorption solution volume. The relative standard deviation of different methyl propyl ketone concentrations was 1.42%∼1.65%, and the recovery rate was 94.9%∼ 97.9%.
Conclusion:
This method has high sensitivity, precision, and accuracy, and it is applicable for determination of methyl propyl ketone in the air of workplace.
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