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Updated: Apr 19, 2026
Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities
Published on: October 27, 2023
4D co-registration of X-ray and MR-mammograms: initial clinical results and potential incremental diagnostic value
Matthias Dietzel1, Torsten Hopp2, Nicole V Ruiter2
1Department of Neuroradiology, University of Erlangen-Nürnberg, Schwabachanlage 6, D-91054, Germany; Institute of Diagnostic and Interventional Radiology I, Friedrich-Schiller-University Jena, Erlanger Allee 101, D-07740 Jena, Germany.
Purpose:
4D co-registration of X-ray- and MR-mammograms (XM and MM) is a new method of image fusion. The present study aims to evaluate its clinical feasibility, radiological accuracy, and potential clinical value.
Methods:
XM and MM of 25 patients were co-registered. Results were evaluated by a blinded reader.
Results:
Precision of the 4D co-registration was "very good" (mean-score [ms]=7), and lesions were "easier to delineate" (ms=5). In 88.8%, "relevant additional diagnostic information" was present, accounting for a more "confident diagnosis" in 76% (ms=5).
Conclusion:
4D co-registration is feasible, accurate, and of potential clinical value.
