Related Experiment Video
Updated: Apr 19, 2026
A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing Neoadjuvant Therapies
Published on: July 28, 2020
Role of radiation therapy for non-extremity soft tissue sarcomas
Karen De Amorim Bernstein1, Thomas F Delaney
1Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts.
Background:
Negative surgical margins are uncommon for non-extremity soft tissue sarcomas. Radiation therapy is usually recommended to improve local control; however, appropriate RT dosing is challenging due to nearby dose-limiting normal structures.
Material And Methods:
Comprehensive literature search using PubMed (March 2014).
Results:
Data suggest radiation therapy is an important modality in maximizing local tumor control in non-extremity sarcomas.
Conclusion:
The literature supports the use of RT to improve local control for non-extremity soft tissue sarcomas.
