From a Cell's Viewpoint: Targeting Mitochondria in Alzheimer's disease
Emily Ann Carlson1, Valasani Koteswara Rao1, Shirley ShiDu Yan1
1Department of Pharmacology & Toxicology and Higuchi Biosciences Center, School of Pharmacy, University of Kansas, Lawrence, Kansas 66047, USA.
Abstract:
Mitochondria are well-known cellular organelles widely studied in relation to a variety of disease states, including Alzheimer's disease. With roles in several metabolic processes, numerous signal transduction pathways, and overall cell maintenance and survival, mitochondria are essential to understanding the inner workings of cells. As mitochondria are able to be utilized by diverse illnesses to increase the likelihood of disease progression, targeting specific processes in these organelles could provide beneficial therapeutic options.
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