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A Flow Cytometry-Based Cell Surface Protein Binding Assay for Assessing Selectivity and Specificity of an Anticancer Aptamer
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Therapeutic aptamers: developmental potential as anticancer drugs

Ji Won Lee1, Hyun Jung Kim1, Kyun Heo1

  • 1Research Institute, National Cancer Center, Goyang 410-769, Korea.

BMB Reports
|January 7, 2015
PubMed
Summary

Aptamers, or DNA/RNA molecules, show promise as cancer therapeutics due to their specificity and low toxicity. Current clinical trials are evaluating aptamer-based treatments targeting nucleolin and CXCL12 for cancer patients.

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