It takes two to rule translation elongation
Related Experiment Video
Updated: Apr 18, 2026

Artificial RNA Polymerase II Elongation Complexes for Dissecting Co-transcriptional RNA Processing Events
Published on: May 13, 2019
1Structural Biology Brussels, Vrije Universiteit Brussel (VUB), 1050 Brussels, Belgium; Structural Biology Research Center, VIB, 1050 Brussels, Belgium.
Abstract:
In this issue of Structure, Glatt and colleagues report the structure of the Kti11/Kti13 heterodimer. This study reveals how dimerization and Fe(2+) binding are required for modification of both tRNA and EF2, thus suggesting a mechanism for regulation of translation elongation via two different pathways.
Related Concept Videos
Transcription Elongation Factors
The transcription elongation is regulated via pausing of RNA polymerase on several occasions during transcription. In bacteria, these halts are necessary because the transcription of DNA into mRNA is coupled to the translation of that mRNA...
Transcription Elongation Factors
Transcription Initiation
The promoters and enhancers and their accessory proteins allow tight regulation of...
Bacterial Transcription
Transcription can be divided into three main stages, each involving distinct DNA sequences to guide the polymerase. These are:
Transcription
Transcription Can Produce Different Kinds of RNA Molecules
In eukaryotes,...
Transcription
Transcription is the process of synthesizing RNA from a DNA sequence by RNA polymerase. It is the first step in producing a protein from a gene sequence. Additionally, many other proteins and regulatory sequences are involved in the proper synthesis of messenger RNA (mRNA). Regulation of transcription is responsible for the differentiation of all the different types of cells and often for the proper cellular response to environmental signals.
Transcription Can Produce Different Kinds...

