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Efficacy of green tea extract in two exercise models
A V Novozhilov1, T V Tavrovskaya, N G Voitenko
1I. M. Sechenov Institute for Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, Russia, artnov20081@rambler.ru.
Bulletin of Experimental Biology and Medicine
|January 10, 2015
Summary
Green tea extract supplementation improved endurance in rats. Higher doses normalized iron levels and spleen weight, suggesting benefits for blood formation and antioxidant defense.
Area of Science:
- Exercise Physiology
- Nutritional Biochemistry
- Pharmacology
Background:
- Exercise can induce physiological stress, affecting hematological parameters and antioxidant status.
- Green tea extract (GTE) contains bioactive compounds with potential ergogenic and antioxidant properties.
Purpose of the Study:
- To investigate the effects of oral green tea extract on exercise performance and hematological parameters in rats.
- To evaluate the impact of different GTE dosages and administration frequencies on endurance and physiological markers.
Main Methods:
- Rats were administered GTE orally at 6 mg/kg twice daily or 12 mg/kg once daily for two weeks.
- Exercise performance was assessed via swimming and exhaustive running tests.
- Hematological parameters including spleen weight, serum iron, reticulocytosis, and erythrocyte glutathione levels were measured.
Main Results:
- GTE at 6 mg/kg significantly increased swimming times.
- Exhaustive running led to decreased spleen weight and serum iron, with increased reticulocytosis.
- GTE at 12 mg/kg prevented the decrease in serum iron and spleen weight, and increased erythrocyte glutathione.
Conclusions:
- Green tea extract demonstrates potential ergogenic benefits, enhancing endurance performance.
- GTE may exert a normalizing effect on hemopoiesis and stimulate the antioxidant system in erythrocytes, particularly at higher doses.
- These findings suggest GTE could be a beneficial supplement for athletes or individuals undergoing strenuous physical activity.

