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Updated: Apr 18, 2026

A Miniaturized Glycan Microarray Assay for Assessing Avidity and Specificity of Influenza A Virus Hemagglutinins
Published on: May 29, 2016
Determination of receptor specificities for whole influenza viruses using multivalent glycan arrays
Mia L Huang1, Miriam Cohen, Christopher J Fisher
1Department of Chemistry and Biochemistry, University of California San Diego, 9500 Gilman Drive, San Diego, CA 92093-0358, USA. kgodula@ucsd.edu.
Abstract:
Influenza viruses bind to mucosal glycans to gain entry into a host organism and initiate infection. The target glycans are often displayed in multivalent arrangements on proteins; however, how glycan presentation influences viral specificity is poorly understood. Here, we report a microarray platform approximating native glycan display to facilitate such studies.
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