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Related Concept Videos

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Dermis
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Related Experiment Video

Updated: Apr 18, 2026

Microdissection of Black Widow Spider Silk-producing Glands
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Spiders in dermatology.

Jun K Kang1, Chinmoy Bhate, Robert A Schwartz

  • 1Dermatology, Rutgers New Jersey Medical School, Newark, NJ, USA.

Seminars in Cutaneous Medicine and Surgery
|January 13, 2015
PubMed
Summary

Spider bites are rarely a serious medical concern, despite common fears. Most spider-related skin reactions in the US are mild and manageable with basic care, with few species posing significant risk.

Area of Science:

  • Dermatology
  • Toxicology
  • Arachnology

Background:

  • Spider bites are frequently diagnosed but often misdiagnosed.
  • Arachnophobia (fear of spiders) is common, yet few spider species are medically significant.
  • Most spider-related skin issues result in localized symptoms.

Purpose of the Study:

  • To review medically relevant spiders encountered in the United States.
  • To aid dermatologists in diagnosing and managing suspected spider bites.
  • To differentiate true spider envenomations from other dermatological conditions.

Main Methods:

  • Literature review of medically significant spider families.
  • Clinical case review of presentations related to spider encounters.
  • Differential diagnosis discussion for cutaneous reactions.

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Main Results:

  • Only a small proportion of spider families (Araneae) are considered medically relevant.
  • Most cutaneous reactions to spiders involve mild, localized symptoms.
  • Accurate identification of the spider is often lacking, complicating diagnosis.

Conclusions:

  • Spider bites are an over-diagnosed condition in clinical practice.
  • Dermatologists should be aware of the limited number of medically significant spiders in the US.
  • Management typically involves supportive care for mild, localized symptoms.