Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Emergent cytotoxicity and mitochondrial alterations induced by a heterobimetallic Re(I)/Au(I) complex.

Chemical communications (Cambridge, England)·2026
Same author

Patient-derived glioblastoma cultures preserve respiration phenotypes during ex vivo maintenance and show sex-associated differences in migration.

Acta neuropathologica communications·2026
Same author

Determinants of malnutrition in older hospitalized patients: a prospective multicenter study with the DoMAP model.

BMC geriatrics·2026
Same author

Comparison of laryngeal tube evo with tracheal intubation during intra-arrest-ventilation using biphasic positive pressure ventilation - a prospective randomized controlled body donor study.

Critical care (London, England)·2026
Same author

Progesterone Receptor Expression in the Human Enteric Nervous System.

International journal of molecular sciences·2026
Same author

Sex hormones, the gut microbiome, and neurodegenerative diseases: Lifespan perspective.

Neural regeneration research·2025

Related Experiment Video

Updated: Apr 18, 2026

Temporal Ordering of Dynamic Expression Data from Detailed Spatial Expression Maps
11:52

Temporal Ordering of Dynamic Expression Data from Detailed Spatial Expression Maps

Published on: February 9, 2017

6.6K

Spatiotemporal expression of Math6 during mouse embryonic development.

Baigang Wang1, Ajeesh Balakrishnan-Renuka, Markus Napirei

  • 1Department of Cytology, Ruhr-University Bochum, Universitätsstrasse 150, 44801, Bochum, Germany.

Histochemistry and Cell Biology
|January 13, 2015
PubMed
Summary

This study maps Math6 expression during mouse embryonic development, revealing its role in organogenesis. Math6 is crucial for multiple developmental events from early stages through late organ formation.

More Related Videos

Electroporation of the Hindbrain to Trace Axonal Trajectories and Synaptic Targets in the Chick Embryo
10:04

Electroporation of the Hindbrain to Trace Axonal Trajectories and Synaptic Targets in the Chick Embryo

Published on: May 29, 2013

11.5K
In vitro Electroporation of the Lower Rhombic Lip of Midgestation Mouse Embryos
07:53

In vitro Electroporation of the Lower Rhombic Lip of Midgestation Mouse Embryos

Published on: August 3, 2012

10.9K

Related Experiment Videos

Last Updated: Apr 18, 2026

Temporal Ordering of Dynamic Expression Data from Detailed Spatial Expression Maps
11:52

Temporal Ordering of Dynamic Expression Data from Detailed Spatial Expression Maps

Published on: February 9, 2017

6.6K
Electroporation of the Hindbrain to Trace Axonal Trajectories and Synaptic Targets in the Chick Embryo
10:04

Electroporation of the Hindbrain to Trace Axonal Trajectories and Synaptic Targets in the Chick Embryo

Published on: May 29, 2013

11.5K
In vitro Electroporation of the Lower Rhombic Lip of Midgestation Mouse Embryos
07:53

In vitro Electroporation of the Lower Rhombic Lip of Midgestation Mouse Embryos

Published on: August 3, 2012

10.9K

Area of Science:

  • Developmental Biology
  • Gene Expression Analysis
  • Molecular Biology

Background:

  • The transcription factor Math6 (basic helix-loop-helix) has known regulatory roles in development.
  • A comprehensive map of Math6 expression throughout mouse embryogenesis is currently unavailable.

Purpose of the Study:

  • To systematically document Math6 expression patterns during mouse embryonic development.
  • To provide insights into Math6's regulatory functions in mouse organogenesis.

Main Methods:

  • Immunohistochemistry was employed to detect Math6 protein expression.
  • Analysis of Math6 expression in transgenic mouse embryos (EGFP-Cre reporter) was performed.

Main Results:

  • Math6 expression was detected in the inner cell mass at the blastocyst stage.
  • Expression was observed in the neural tube, mesoderm, myotome, pharyngeal arches, foregut, heart, brain, limb buds, and liver across various embryonic stages (E8.5-E12.5).
  • Later stage analysis using EGFP revealed Math6 expression in the neural tube, heart, lung, skeletal muscle, skin, cartilage, trachea, and aorta.

Conclusions:

  • Math6 exhibits dynamic expression across numerous organs during mouse embryonic development.
  • These findings highlight Math6's involvement in diverse developmental processes and organogenesis.