Giant fibro-adenomas in black and Indian adolescents

Over a 5-year period, 47 giant fibro-adenomas were managed in the benign breast clinic at King Edward VIII Hospital, Durban. These tumours usually present in the perimenarchal period with gross breast asymmetry; smaller fibro-adenomas are present in 10% of these patients. A hormonal basis for their development is likely. Local excision with preservation of the breast tissue is recommended.