Related Experiment Video
Updated: Apr 18, 2026
12:57
X-Ray Visualization of Intraductal Ethanol-Based Ablative Treatment for Prevention of Breast Cancer in Rat Models
Published on: December 9, 2022
2.9K
Unusually high prolactin level for medication-induced hyperprolactinemia: a case report
Emin M Akbas1, Adem Gungor1, Cigdem Ozdemir1
1Atatürk University, Faculty of Medicine, Department of Internal Medicine, Division of Endocrinology and Metabolism, Erzurum, Turkey.
The Eurasian Journal of Medicine
|January 23, 2015
Summary
Medication-induced hyperprolactinemia can cause high prolactin levels. A rare case highlights extremely elevated prolactin from combining an antipsychotic and antidepressant.
Area of Science:
- Endocrinology
- Pharmacology
Background:
- Hyperprolactinemia, elevated prolactin levels, stems from various causes including physiological, pathological, and pharmacological factors.
- Medication-induced hyperprolactinemia is common, typically resulting in mild elevations (prolactin < 100 ng/mL).
Observation:
- This report details a 43-year-old woman presenting with exceptionally high prolactin levels.
- The patient was concurrently using sulpiride, an antipsychotic, and paroxetine, an antidepressant.
Findings:
- The combination of sulpiride and paroxetine induced severe hyperprolactinemia, exceeding typical levels seen with single-drug use.
- This case demonstrates a rare instance of extreme prolactin elevation due to a drug combination.
Implications:
- Clinicians should consider drug interactions when evaluating patients with medication-induced hyperprolactinemia.
- This case underscores the importance of a thorough medication review in managing hyperprolactinemia.
