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Updated: Apr 18, 2026

Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists
Published on: November 15, 2013
Nuclear Receptor Signaling: a home for nuclear receptor and coregulator signaling research
Neil J McKenna1, Ronald M Evans1, Bert W O'Malley1
1Nuclear Receptor Signaling Atlas (NJM, RME, BWO) and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030 (NJM, BWO), and Gene Expression Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037 (RME).
Abstract:
The field of nuclear receptor and coregulator signaling has grown into one of the most active and interdisciplinary in eukaryotic biology. Papers in this field are spread widely across a vast number of journals, which complicates the task of investigators in keeping current with the literature in the field. In 2003, we launched Nuclear Receptor Signaling as an Open Access reviews, perspectives and methods journal for the nuclear receptor signaling field. Building on its success and impact on the community, we have added primary research and dataset articles to this list of article categories, and we now announce the re-launch of the journal this month. Here we will summarize the rationale that informed the creation and expansion of the journal, and discuss the possibilities for its future development.
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