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[Hydroxyapatite implant for human periodontal osseous defects]
Nihon Shishubyo Gakkai Kaishi
|March 1, 1989
Summary
Porous hydroxyapatite (HAP) effectively treats periodontal defects, showing significant attachment gain and reduced pocket depth. Careful application is advised for specific complex cases like one-wall defects.
Area of Science:
- Biomaterials Science
- Periodontology
- Regenerative Medicine
Context:
- Periodontitis leads to significant tooth-supporting bone loss.
- Current treatments aim to regenerate lost periodontal tissues.
- Hydroxyapatite (HAP) is a synthetic bone substitute with potential for periodontal regeneration.
Purpose:
- To assess the clinical efficacy of porous hydroxyapatite (HAP) as an implant material in human periodontal osseous defects.
Summary:
- Porous hydroxyapatite (HAP) granules and blocks were implanted into 44 periodontal defects in 33 patients with marginal periodontitis.
- Post-implantation, gingival inflammation, open wounds, and HAP discharge resolved quickly without complications.
- Radiographic analysis showed integration of HAP with alveolar bone.
- At six months, mean gingival recession was 0.9 mm, pocket depth reduction was 2.7 mm, and clinical attachment gain was 1.9 mm, reaching 2.0 mm beyond six months.
Impact:
- Porous hydroxyapatite (HAP) demonstrates clinical effectiveness in periodontal defect treatment.
- Achieved significant clinical attachment gain and pocket depth reduction.
- Results suggest HAP is a viable option, though caution is recommended for one-wall osseous defects and furcation involvements.