Related Experiment Video
Updated: Apr 18, 2026

Achieving Moderate Pressures in Sealed Vessels Using Dry Ice As a Solid CO2 Source
Published on: August 17, 2018
An inexpensive replacement for dry ice in the laboratory
1Program in Physical Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health (NIH), Bethesda, MD 20892, USA.
Researchers developed a reusable, inexpensive laboratory alternative to dry ice. Small stone or metal pellets stored in a -80°C freezer offer faster freezing rates for samples and can be reused after re-chilling.
Area of Science:
- Laboratory Science
- Materials Science
Background:
- Dry ice (solid carbon dioxide) is a common laboratory coolant.
- Dry ice requires specialized handling and storage.
- Limitations exist for dry ice in certain laboratory applications.
Purpose of the Study:
- To present a cost-effective and reusable alternative to dry ice for laboratory sample freezing.
- To evaluate the freezing efficiency of the proposed alternative compared to dry ice.
Main Methods:
- Utilizing commercially available small pellets of stone or metal.
- Storing these pellets in a -80 °C freezer.
- Employing the chilled pellets for rapid freezing of small laboratory samples.
Main Results:
- The developed method provides a faster freezing rate than traditional dry ice.
- The stone or metal pellets are reusable after being returned to the freezer.
- The alternative is inexpensive and readily available.
Conclusions:
- Stone or metal pellets stored at -80 °C offer a practical, efficient, and reusable replacement for dry ice in laboratory settings.
- This method enhances laboratory sample preparation by providing a superior freezing rate.
- The approach presents a sustainable and economical solution for common laboratory cooling needs.
More Related Videos
05:47Do-It-Yourself Device for Recovery of Cryopreserved Samples Accidentally Dropped into Cryogenic Storage Tanks
Published on: May 11, 2012
06:06A Simple Dewar/Cryostat for Thermally Equilibrating Samples at Known Temperatures for Accurate Cryogenic Luminescence Measurements
Published on: July 19, 2016
Related Concept Videos
Phase Transitions: Sublimation and Deposition
Sublimation
Noble Gases
The elements in group 18 are noble gases (helium, neon, argon, krypton, xenon, and radon). They earned the name “noble” because they were assumed to be nonreactive since they have filled valence shells. In 1962, Dr. Neil Bartlett at the University of British Columbia proved this assumption to be false.