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Updated: Aug 5, 2026

Application of Elemental Lanthanides in the Selective C-F Activation of Trifluoromethylated Benzofulvenes Providing Access to Various Difluoroalkenes
10:10

Application of Elemental Lanthanides in the Selective C-F Activation of Trifluoromethylated Benzofulvenes Providing Access to Various Difluoroalkenes

Published on: July 28, 2018

Nickel-Catalyzed Three-Component Difluoroalkylation-Amination for the Direct Access to Anti-Inflammatory

Chang Xu1, Fangting Ma1, Fan Ding1,2

  • 1School of Pharmaceutical Sciences and Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming, Yunnan, People's Republic of China.

Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
|August 3, 2026
PubMed

Keywords:
SH2‐type reactionanti‐inflammationcarboaminationin vitro and in vivo studynickel catalysisβ‐difluoroalkyl amines

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