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Published on: June 13, 2017
Analysis of therapeutic methods for treating vocal process granulomas
Lijing Ma1, Yang Xiao, Jingying Ye
1Key Laboratory of Otolaryngology Head and Neck Surgery (Ministry of Education of China), Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University , Beijing , China.
Vocal process granulomas (VPGs) treatment combining surgery and botulinum toxin type A (BTA) injections shows higher cure rates. This approach offers an effective solution for patients unresponsive to conservative therapies.
Area of Science:
- Otolaryngology
- Laryngology
Background:
- Vocal process granulomas (VPGs) are benign lesions that can cause significant voice impairment.
- Conservative treatments, including acid suppression, vocal rest, and voice therapy, are often the first line of management for VPGs.
Purpose of the Study:
- To evaluate the efficacy of conservative treatments, microsurgical resection with suturing, and microsurgery combined with botulinum toxin type A (BTA) injections for VPGs.
Main Methods:
- A retrospective analysis of 168 VPG cases was conducted.
- Patients initially received conservative treatment; non-responders underwent microsurgical resection with suturing or microsurgery with BTA injections.
Main Results:
- Conservative treatments led to lesion disappearance in 41.3% and reduction in 10.7% of patients.
- Microsurgical resection achieved a 78.4% cure rate.
- The combination of microsurgery and BTA injections resulted in a 95.2% cure rate with low recurrence.
Conclusions:
- Combining laryngeal microsurgery with local botulinum toxin type A (BTA) injections significantly improves cure rates for vocal process granulomas (VPGs).
- This combined approach offers a highly effective treatment option for VPGs, particularly for cases refractory to conservative management.
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