Related Experiment Video
Updated: Apr 17, 2026

10:46
Doppler Optical Coherence Tomography of Retinal Circulation
Published on: September 18, 2012
19.4K
Repeatability and reproducibility of a double-pass optical quality analysis device.
Chen-Chen Xu1, Ting Xue1, Qin-Mei Wang1
1The Eye Hospital of Wenzhou Medical University, Wenzhou, China.
Plos One
|February 4, 2015
Summary
The OQASII system demonstrates excellent repeatability and good reproducibility for objective measurements of human eye optical quality in clinical settings. This validates its reliability for assessing visual performance.
Area of Science:
- Ophthalmology
- Optometry
- Vision Science
Background:
- Objective measurement of human eye optical quality is crucial for understanding visual performance.
- The double-pass instrument OQASII offers a method for such assessments.
Purpose of the Study:
- To evaluate the repeatability and reproducibility of the OQASII system for objective optical quality measurements.
- To assess the reliability of OQASII in a clinical setting with healthy subjects.
Main Methods:
- 119 healthy subjects with good visual acuity were included.
- Measurements were taken by two examiners on the same day and again a week later.
- Repeatability and reproducibility of modulation transfer function cutoff (MTF cutoff), Strehl ratio, OQAS values (OVs), and objective scatter index (OSI) were analyzed.
Main Results:
- The OQASII system showed good repeatability and reproducibility across all measured parameters.
- High interclass correlation coefficients (>0.88) and low coefficients of variation were observed.
- Bland-Altman analysis confirmed good agreement and narrow limits of agreement for inter-observer and inter-visit measurements.
Conclusions:
- The OQASII system provides excellent repeatability and good reproducibility for objective optical quality assessment.
- The findings support the clinical utility of OQASII for reliable eye optical quality measurements.

