Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Attention-Deficit/Hyperactivity Disorder

Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....

Altered States of Awareness

Altered States of Awareness

Altered states of consciousness represent significant deviations from one's normal mental state. These deviations can range from subtle changes in awareness to profound transformations in perception, thought processes, and sensory experiences. Altered states of consciousness can be triggered by various factors, including drug use, meditation, hypnosis, illness, or even intense fatigue.
The ingestion of substances like stimulants or hallucinogens leads to chemical alterations in the brain...

Autism Spectrum Disorder

Autism Spectrum Disorder

Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Smartphone-based detection of subtle memory decline in prodromal Alzheimer's disease.

NPJ digital medicine·2026

Same author

Subjective cognition trajectories, Alzheimer biomarkers, and incident mild cognitive impairment.

The journal of prevention of Alzheimer's disease·2026

Same author

Gene deletion of Klotho in the dentate gyrus does not affect the number of adult-born granule cells.

Scientific reports·2026

Same author

Minor neuropsychological deficits and stage 2 of Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026

Same author

Non-economic social deprivation and cognitive functioning later in life: Results from the DELCODE study.

Journal of Alzheimer's disease : JAD·2026

Same author

Alzheimer's Disease Co-Pathology and Cognitive Impairment in Amyotrophic Lateral Sclerosis.

Annals of neurology·2026

Same journal

Neural Markers of Interocular Grouping During Binocular Rivalry With MEG.

Human brain mapping·2026

Same journal

Neural Correlates of Explicit Outcome Expectation Effects: An Activation Likelihood Estimation Meta-Analysis.

Human brain mapping·2026

Same journal

Benchmarking fMRI Denoising Pipelines.

Human brain mapping·2026

Same journal

Modeled Long-Term Effects of Psilocybin on Dynamic Activity and Effective Connectivity of Fronto-Striatal-Thalamic Circuits.

Human brain mapping·2026

Same journal

Intrinsic Functional Architecture Reflects Individual Differences in Passive Working Memory: An Exploratory Resting-State fMRI Study.

Human brain mapping·2026

Same journal

Symptom Overlap and Neurobiological Similarities Between Posttraumatic Stress Disorder and Tinnitus.

Human brain mapping·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Apr 17, 2026

Comparing Eye-tracking Data of Children with High-functioning ASD, Comorbid ADHD, and of a Control Watching Social Videos

Comparing Eye-tracking Data of Children with High-functioning ASD, Comorbid ADHD, and of a Control Watching Social Videos

Published on: December 7, 2018

Altered salience processing in attention deficit hyperactivity disorder.

Jana Tegelbeckers¹, Nico Bunzeck, Emrah Duzel

¹Department of Child and Adolescent Psychiatry and Psychotherapy, Otto von Guericke University, Magdeburg, Germany.

Human Brain Mapping

|February 5, 2015

Summary

This summary is machine-generated.

Children with attention deficit hyperactivity disorder (ADHD) show heightened brain responses to novel stimuli and reduced habituation to familiar ones, suggesting inefficient neural resource use and increased distractibility.

Keywords:

attention deficit hyperactivity disorder distraction fMRI novelty oddball

More Related Videos

The Adventures of Fundi Intervention Based on the Cognitive and Emotional Processing in Attention Deficit Hyperactive Disorder Patients

The Adventures of Fundi Intervention Based on the Cognitive and Emotional Processing in Attention Deficit Hyperactive Disorder Patients

Published on: June 12, 2020

Measuring Attention and Visual Processing Speed by Model-based Analysis of Temporal-order Judgments

Measuring Attention and Visual Processing Speed by Model-based Analysis of Temporal-order Judgments

Published on: January 23, 2017

Related Experiment Videos

Last Updated: Apr 17, 2026

Comparing Eye-tracking Data of Children with High-functioning ASD, Comorbid ADHD, and of a Control Watching Social Videos

Comparing Eye-tracking Data of Children with High-functioning ASD, Comorbid ADHD, and of a Control Watching Social Videos

Published on: December 7, 2018

The Adventures of Fundi Intervention Based on the Cognitive and Emotional Processing in Attention Deficit Hyperactive Disorder Patients

The Adventures of Fundi Intervention Based on the Cognitive and Emotional Processing in Attention Deficit Hyperactive Disorder Patients

Published on: June 12, 2020

Measuring Attention and Visual Processing Speed by Model-based Analysis of Temporal-order Judgments

Measuring Attention and Visual Processing Speed by Model-based Analysis of Temporal-order Judgments

Published on: January 23, 2017

Area of Science:

Neuroscience
Developmental Psychology
Cognitive Science

Background:

Attentional problems in attention deficit hyperactivity disorder (ADHD) are often linked to cognitive control deficits.
The relationship between these deficits and sensitivity to external salient stimuli is not fully understood.

Purpose of the Study:

To investigate neural responses to novelty and familiarity in boys with and without ADHD.
To differentiate the effects of item novelty, contextual rareness, and task relevance on brain activity.

Main Methods:

Functional magnetic resonance imaging (fMRI) was used to scan 38 boys (aged 11-16) with and without ADHD.
Participants performed a visual oddball task with four stimulus categories: standard, novel, rare familiar, and target.

Main Results:

Both groups showed overlapping novelty-related brain responses.
Healthy participants exhibited neural deactivation in response to novel pictures, unlike ADHD patients.
ADHD patients engaged broader novelty network regions for rare familiar pictures, indicating reduced habituation.

Conclusions:

ADHD patients exhibit enhanced neural activity to behaviorally irrelevant novel stimuli and reduced habituation to familiar items.
Findings suggest inefficient neuronal resource utilization in children with ADHD, potentially explaining increased distractibility.