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Updated: Apr 17, 2026
Dissection, Immunohistochemistry and Mounting of Larval and Adult Drosophila Brains for Optic Lobe Visualization
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Common temporal identity factors regulate neuronal diversity in fly ventral nerve cord and mouse retina
Nikolaos Konstantinides1, Anthony M Rossi1, Claude Desplan1
1Department of Biology, New York University, 1009 Silver Center, 100 Washington Square East, New York, NY 10003, USA.
Abstract:
Temporal sequences of transcription factors (tTFs) in Drosophila neural progenitors generate neuronal diversity. Mattar et al. (2015) identify Casz1/Castor as a late temporal identity factor in mouse retinal progenitors that is regulated by the early factor Ikzf1/Hunchback, thus generalizing the notion of tTFs.
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