Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Radical Formation: Homolysis

Radical Formation: Homolysis

A bond is formed between two atoms by sharing two electrons. When this bond is broken by supplying sufficient energy, either two electrons can be taken up by one atom forming ions by the cleavage called heterolysis, or the two electrons are shared by two atoms, with one each creating radicals by the cleavage called homolysis.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Substituent effects direct anion transport in aryl-triazole derivatives.

Organic & biomolecular chemistry·2026

Same author

Photosensitive and extracellular matrix-mimicking hydrogels promote the tendon-bone healing in rotator cuff injury.

Journal of materials science. Materials in medicine·2026

Same author

Visible-Light-Catalyzed Cascade Radical Cyclization for 3-Substituted Chroman-4-ones.

The Journal of organic chemistry·2025

Same author

Reversible Zn<sup>2+</sup>-Activated Channel Transport Through Monomer-Dimer Interconversion of Rotaxane.

Angewandte Chemie (International ed. in English)·2025

Same author

Investigation into the rockfall impact process of a quarry landfill slope under highway expansion.

Natural hazards (Dordrecht, Netherlands)·2025

Same author

Triphenylphosphine-Initiated Ring-Opening Polymerization for α-Helical Polypeptides and Application in Constructing Artificial Ion Channels.

Biomacromolecules·2025

Search research articles

Related Experiment Video

Updated: Apr 17, 2026

Solvent Bonding for Fabrication of PMMA and COP Microfluidic Devices

Solvent Bonding for Fabrication of PMMA and COP Microfluidic Devices

Published on: January 17, 2017

Building biomedical materials using photochemical bond cleavage.

Chunyan Bao¹, Linyong Zhu, Qiuning Lin

¹Key Laboratory for Advanced Materials, Institute of Fine Chemicals, East China University of Science and Technology, 130# Meilong Road, Shanghai, 200237, China.

Advanced Materials (Deerfield Beach, Fla.)

|February 7, 2015

Summary

This summary is machine-generated.

Phototriggers use light to initiate processes, enabling photoactivation, degradation, and drug release. Improvements are needed for advanced biomedical applications requiring better sensitivity and faster kinetics.

Keywords:

biomedical materials photoactivation photocleavage photorelease phototriggers

More Related Videos

Bridging the Bio-Electronic Interface with Biofabrication

Bridging the Bio-Electronic Interface with Biofabrication

Published on: June 6, 2012

Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold

Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold

Published on: October 23, 2015

Related Experiment Videos

Last Updated: Apr 17, 2026

Solvent Bonding for Fabrication of PMMA and COP Microfluidic Devices

Solvent Bonding for Fabrication of PMMA and COP Microfluidic Devices

Published on: January 17, 2017

Bridging the Bio-Electronic Interface with Biofabrication

Bridging the Bio-Electronic Interface with Biofabrication

Published on: June 6, 2012

Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold

Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold

Published on: October 23, 2015

Area of Science:

Chemistry
Materials Science
Biomedical Engineering

Background:

Light offers precise spatiotemporal control over chemical and biological processes.
Phototriggers are photoresponsive molecules that break chemical bonds upon light exposure.
Key functions include photoactivation, photocleavage, and photorelease for various applications.

Purpose of the Study:

To review advancements in phototrigger technology.
To discuss improvements in phototrigger sensitivity and kinetics.
To highlight biomedical applications and associated challenges.

Main Methods:

Review of conventional phototrigger improvements.
Analysis of representative biomedical applications.
Discussion of current challenges and future directions.

Main Results:

Conventional phototriggers have been enhanced for improved performance.
Notable biomedical applications demonstrate the utility of phototriggers.
Specific challenges remain for demanding in vivo applications.

Conclusions:

Phototrigger technology is crucial for light-controlled processes.
Ongoing improvements are essential for advanced biomedical applications.
Further research is needed to overcome limitations in sensitivity and kinetics.