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Dopaminergic Neurogenetics of Sleep Disorders in Reward Deficiency Syndrome (RDS)
Kenneth Blum1, Marlene Oscar-Berman2, Rajendra D Badgaiyan3
1Department of Psychiatry, & McKnight Brain Institute, University of Florida College of Medicine, Gainesville, Florida, USA ; Department of Addiction Research & Therapy, Malibu Beach Recovery Center, Malibu Beach, California, USA ; Department of Nutrigenomics, IGENE, LLC, Austin, Texas, USA ; Dominion Diagnostics, LLC ., North Kingstown, Rhode Island, USA ; Department of Clinical Neurology, PATH Foundation NY., USA.
Abstract:
It is well-known that sleep has a vital function especially as it relates to prevention of substance-related disorders as discussed in the DSM-V. We are cognizant that certain dopaminergic gene polymorphisms have been associated with various sleep disorders. The importance of "normal dopamine homeostasis" is tantamount for quality of life especially for the recovering addict. Since it is now know that sleep per se has been linked with metabolic clearance of neurotoxins in the brain, it is parsonomiuos to encourage continued research in sleep science, which should ultimately result in attenuation of sleep deprivation especially associated with substance related disorders.
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