Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Toxidromes: Clinical Features01:30

Toxidromes: Clinical Features

157
Toxidromes are specific patterns of symptoms resulting from toxic substance exposure. They help in the identification and treatment of poisoning. The symptoms of each toxidrome group indicate poisoning by a certain class of chemicals or drugs.1. Sympathomimetic: Stimulates the sympathetic nervous system. Symptoms include agitation, increased heart rate (HR), blood pressure (BP), respiratory rate (RR), temperature, and pupil size. Drugs like cocaine and amphetamines, along with tremors and...
157
Diphtheria01:28

Diphtheria

146
Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...
146
Anticholinesterase Agents: Poisoning and Treatment01:26

Anticholinesterase Agents: Poisoning and Treatment

2.0K
Anticholinesterases, also known as cholinesterase inhibitors, work by blocking the breakdown of acetylcholine, leading to its accumulation in the synaptic cleft. This accumulation indirectly enhances both muscarinic and nicotinic actions. These agents are classified as reversible or irreversible based on their mechanism of action.     
Irreversible agents form a strong bond with the cholinesterase enzyme, making it inactive. The breakdown of the phosphorylated enzyme is...
2.0K
Prevention of Further Absorption of Poison01:14

Prevention of Further Absorption of Poison

1.4K
In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using various decontamination techniques targeting the gastrointestinal (GI) tract can achieve this. Decontamination is crucial to prevent poison from entering the systemic circulation, which involves washing affected areas with water and mild soap and removing contaminated clothing. Once external decontamination is done, attention must be turned to...
1.4K
Drug Toxicity: Overview01:00

Drug Toxicity: Overview

259
Drug toxicity quantifies the harm a compound causes to an organism, varying by dose and potentially impacting whole systems or specific organs like the liver. Toxic reactions may arise from venomous insect or spider bites, with effects ranging from mild symptoms to severe outcomes such as brain damage or death. Common forms of acute poisoning include ethanol intoxication and overdose of pain or fever medications, with substances like GHB and heroin being particularly lethal at doses close to...
259

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Trained immunity: Breaking a dogma and a missing opportunity in IBD?

Inflammatory bowel diseases·2026
Same author

Semaglutide and Its Potential Hepatoprotective Effects Against Acute Drug-Induced Liver Injury.

Cureus·2026
Same author

Ole-4, a novel synthetic derivative of Oleuropein, enhances antitumor immunity and modulates kinase activity-dependent signaling.

Journal of translational medicine·2026
Same author

Augmented and Mixed Reality in Cardiac Surgery: A Narrative Review.

Journal of clinical medicine·2026
Same author

A Narrative Review on Current Status of Conscious Sedation for Transcatheter Aortic Valve Implantation.

Medicina (Kaunas, Lithuania)·2025
Same author

Multi-country surveillance of paediatric invasive group A <i>Streptococcus</i> infection, European Union/European Economic Area countries, 2022/23 season.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin·2025

Related Experiment Video

Updated: Apr 17, 2026

Extraction of Venom and Venom Gland Microdissections from Spiders for Proteomic and Transcriptomic Analyses
10:25

Extraction of Venom and Venom Gland Microdissections from Spiders for Proteomic and Transcriptomic Analyses

Published on: November 3, 2014

34.9K

Latrodectus envenomation in Greece.

Garyfallia Nikolaos Antoniou1, Dimitrios Iliopoulos2, Rania Kalkouni3

  • 1Epidemiological Nurse in the Emergency Operation Center at the Hellenic Center for Disease Control and Prevention in Athens, Greece. antoniou@keelpno.gr.

The Permanente Journal
|February 10, 2015
PubMed
Summary
This summary is machine-generated.

Seven cases of widow spider bites in Greece were reported, with patients experiencing severe symptoms but fully recovering with supportive care and pain relief. Early recognition of Latrodectus bites is crucial for effective medical management.

More Related Videos

Author Spotlight: Optimizing Scorpion Venom Extraction for Antivenom Production
05:27

Author Spotlight: Optimizing Scorpion Venom Extraction for Antivenom Production

Published on: October 6, 2023

4.7K
Analysis of Iophenoxic Acid Analogues in Small Indian Mongoose Herpestes Auropunctatus Sera for Use as an Oral Rabies Vaccination Biological Marker
11:28

Analysis of Iophenoxic Acid Analogues in Small Indian Mongoose Herpestes Auropunctatus Sera for Use as an Oral Rabies Vaccination Biological Marker

Published on: May 31, 2019

6.4K

Related Experiment Videos

Last Updated: Apr 17, 2026

Extraction of Venom and Venom Gland Microdissections from Spiders for Proteomic and Transcriptomic Analyses
10:25

Extraction of Venom and Venom Gland Microdissections from Spiders for Proteomic and Transcriptomic Analyses

Published on: November 3, 2014

34.9K
Author Spotlight: Optimizing Scorpion Venom Extraction for Antivenom Production
05:27

Author Spotlight: Optimizing Scorpion Venom Extraction for Antivenom Production

Published on: October 6, 2023

4.7K
Analysis of Iophenoxic Acid Analogues in Small Indian Mongoose Herpestes Auropunctatus Sera for Use as an Oral Rabies Vaccination Biological Marker
11:28

Analysis of Iophenoxic Acid Analogues in Small Indian Mongoose Herpestes Auropunctatus Sera for Use as an Oral Rabies Vaccination Biological Marker

Published on: May 31, 2019

6.4K

Area of Science:

  • Toxicology
  • Arachnology
  • Public Health

Background:

  • Widow spiders (genus Latrodectus) are globally distributed, with their venom containing alpha-latrotoxin, a potent neurotoxin affecting mammals.
  • Latrodectus bites can cause significant systemic effects, necessitating prompt medical attention.

Observation:

  • Seven cases of widow spider bites were reported in Greece during the 2011-2012 summer period.
  • Patients presented with severe muscle cramps, weakness, tremor, abdominal pain, and elevated creatinine phosphokinase levels.
  • All patients reported a preceding insect bite, highlighting the importance of accurate bite identification.

Findings:

  • Alpha-latrotoxin is the primary toxin responsible for the observed clinical manifestations.
  • Supportive care and effective pain management are key in treating mild to moderate Latrodectus envenomations.
  • Antivenin was administered to four patients, and all seven individuals recovered fully.

Implications:

  • Healthcare professionals must be adept at recognizing the early signs and symptoms of Latrodectus bites for timely intervention.
  • Hospitalization and antivenin administration should be reserved for severe cases or those with uncontrolled pain.
  • Prompt medical care and symptom management are essential for favorable outcomes in widow spider envenomations.