Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Systemic vasculitis: a temporal bone histopathologic study.

T H Yoon1, M M Paparella, P A Schachern

  • 1Department of Otolaryngology, University of Minnesota Medical School, Minneapolis 55455.

The Laryngoscope
|June 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Template-free synthesis of monolithic carbon xerogels with hierarchical porosity from resorcinol and formaldehyde <i>via</i> hydrothermal reaction.

RSC advances·2022
Same author

Atomic clock performance enabling geodesy below the centimetre level.

Nature·2018
Same author

Multivariate statistical analysis for selecting optimal descriptors in the toxicity modeling of nanomaterials.

Computers in biology and medicine·2018
Same author

Faraday-Shielded dc Stark-Shift-Free Optical Lattice Clock.

Physical review letters·2018
Same author

Prospects for observing and localizing gravitational-wave transients with Advanced LIGO, Advanced Virgo and KAGRA.

Living reviews in relativity·2018
Same author

Hyperpolarizability and Operational Magic Wavelength in an Optical Lattice Clock.

Physical review letters·2018
Same journal

Discrimination of Pairs of Chemosensory Stimuli in Relation to Respiration.

The Laryngoscope·2026
Same journal

What Safety Precautions Are Recommended When Lasering in the Airway?

The Laryngoscope·2026
Same journal

Success of Anterior Ethmoidal Artery Flaps for Nasal Septal Perforation Repair: A Systematic Review.

The Laryngoscope·2026
Same journal

Laryngeal IgG4-Related Disease: A Systematic Review of Clinical Features and Management.

The Laryngoscope·2026
Same journal

Elevated BMI Is Not Associated With Adverse Outcomes in Open Airway Reconstruction.

The Laryngoscope·2026
Same journal

What is the Most Effective Treatment Approach for Vocal Fold Granuloma?

The Laryngoscope·2026
See all related articles

Systemic vasculitis can affect the temporal bone, leading to middle ear inflammation and inner ear fibrosis. Histopathologic changes were observed in Wegener

Area of Science:

  • Otolaryngology
  • Rheumatology
  • Pathology

Background:

  • Systemic vasculitis encompasses diverse disorders affecting blood vessels and linked to immunopathogenesis.
  • Understanding its impact on the temporal bone is crucial for diagnosing and managing related complications.

Observation:

  • Histopathologic analysis of 16 temporal bones from 8 patients with systemic vasculitis (Wegener's granulomatosis, polyarteritis nodosa, systemic lupus erythematosus).

Findings:

  • Otitis media observed in 15 ears; chronic middle ear changes in 10, fibrotic inner ear changes in 2.
  • Wegener's granulomatosis showed granulation tissue near the eustachian tube.
  • Polyarteritis nodosa revealed inflammatory infiltrates and vascular thickening around the facial nerve.
  • Systemic lupus erythematosus cases demonstrated severe inner ear fibrosis and new bone formation.

Related Experiment Videos

Implications:

  • This study provides critical histopathologic evidence of temporal bone involvement in systemic vasculitis.
  • Findings correlate clinical observations of hearing loss with specific structural changes in the temporal bone.
  • Highlights the need for otologic evaluation in patients with systemic vasculitis.