Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Diabetic Retinopathy01:27

Diabetic Retinopathy

5
DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
5
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

11.3K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
11.3K
Alzheimer Disease l: Introduction01:29

Alzheimer Disease l: Introduction

2
Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...
2
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

824
As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
824
iPS Cell Differentiation01:22

iPS Cell Differentiation

3.3K
The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.
3.3K
The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

4.2K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
4.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Retinal arterial macroaneurysm rupture in a 17-year-old: Could cannabis consumption be a risk factor?

Journal francais d'ophtalmologie·2025
Same author

Peripheral polypoidal choroidal vasculopathy in Sorsby fundus dystrophy: Report of two cases.

Journal francais d'ophtalmologie·2021
Same author

[Report of a new case of TINU syndrome].

Journal francais d'ophtalmologie·2019
Same author

Long-term results of low-fluence photodynamic therapy for chronic central serous chorioretinopathy.

Journal francais d'ophtalmologie·2015
Same author

Fundus autofluorescence in a case of occult macular dystrophy.

Bulletin de la Societe belge d'ophtalmologie·2010
Same author

[Crystalline retinopathy].

Bulletin de la Societe belge d'ophtalmologie·2007

Related Experiment Video

Updated: Apr 17, 2026

A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging
09:37

A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging

Published on: July 14, 2016

8.9K

[Age-related macular degeneration].

L Van Bol, F Rasquin

    Revue Medicale De Bruxelles
    |February 14, 2015
    PubMed
    Summary

    Age-related macular degeneration (AMD) is a leading cause of vision loss in older adults. This review covers AMD risk factors, diagnosis, and current and future treatments for this growing public health concern.

    Area of Science:

    • Ophthalmology
    • Gerontology
    • Genetics

    Context:

    • Age-related macular degeneration (AMD) is a primary cause of irreversible blindness in individuals over 65.
    • The prevalence of AMD is increasing due to population aging, posing significant socioeconomic challenges.

    Purpose:

    • To review the risk factors, clinical forms, and diagnostic methods for AMD.
    • To discuss current and emerging therapeutic strategies for managing AMD.

    Summary:

    • AMD is a progressive macular disorder leading to central vision loss, with atrophic and exudative forms.
    • Research is actively pursuing improved diagnosis, management, and novel treatments for AMD.
    • Key aspects covered include risk factors, clinical presentation, diagnostic approaches, and therapeutic interventions.

    More Related Videos

    Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
    10:14

    Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

    Published on: May 26, 2023

    4.5K
    Author Spotlight: Understanding Age-Related Macular Degeneration Pathophysiology with QAF Workflow
    08:54

    Author Spotlight: Understanding Age-Related Macular Degeneration Pathophysiology with QAF Workflow

    Published on: May 26, 2023

    2.3K

    Related Experiment Videos

    Last Updated: Apr 17, 2026

    A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging
    09:37

    A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging

    Published on: July 14, 2016

    8.9K
    Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
    10:14

    Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

    Published on: May 26, 2023

    4.5K
    Author Spotlight: Understanding Age-Related Macular Degeneration Pathophysiology with QAF Workflow
    08:54

    Author Spotlight: Understanding Age-Related Macular Degeneration Pathophysiology with QAF Workflow

    Published on: May 26, 2023

    2.3K

    Impact:

    • This review provides a comprehensive overview to aid clinicians and researchers in understanding and combating AMD.
    • Highlights the urgent need for effective interventions given the rising prevalence and impact of AMD.