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Related Concept Videos

Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
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Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...
The Retina01:32

The Retina

The retina is a layer of nervous tissue at the back of the eye that transduces light into neural signals. This process, called phototransduction, is carried out by rod and cone photoreceptor cells in the back of the retina.

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Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
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[Crystalline retinopathy].

F Rasquin1

  • 1Service d'Ophtalmologie, Hôpital Erasme, Université Libre de Bruxelles, Bruxelles. florence.rasquin@erasme.ulb.ac.be

Bulletin De La Societe Belge D'Ophtalmologie
|August 28, 2007
PubMed
Summary

Crystalline retinopathy involves intraretinal deposits that can cause vision loss. This chapter details toxic crystalline retinopathy caused by drugs like tamoxifen and canthaxanthine.

Area of Science:

  • Ophthalmology
  • Toxicology

Context:

  • Crystalline retinopathy presents with intraretinal crystalline deposits.
  • Deposits may be localized or widespread, potentially causing visual impairment and electrophysiological changes.

Purpose:

  • To describe the toxic effects of specific drugs on the retina.
  • To detail the mechanisms and clinical presentation of drug-induced crystalline retinopathy.

Summary:

  • Crystalline retinopathy is characterized by intraretinal deposits.
  • Etiology dictates deposit location and potential for visual loss.
  • Tamoxifen and canthaxanthine are among the drugs causing this condition.

Impact:

  • Provides a detailed understanding of drug-induced crystalline retinopathy.

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Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
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Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

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Retinal Pathophysiological Evaluation in a Rat Model
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Retinal Pathophysiological Evaluation in a Rat Model

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  • Highlights the importance of identifying causative agents for appropriate management.
  • Contributes to the literature on ocular toxicology and retinal diseases.