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Updated: Apr 17, 2026

Author Spotlight: Metallic Nanocomposites to Eliminate Antibiotic-Resistant Bacteria
Published on: October 4, 2024
Antibacterial and non-cytotoxic effect of nanocomposites based in polyethylene and copper nanoparticles
L A Tamayo1, P A Zapata, F M Rabagliati
1Departamento de Química de los Materiales, Facultad de Química y Biología, Universidad de Santiago de Chile, Av. L. B. O`Higgins 3363, Casilla 40, Correo 33, Santiago, Chile, laura.tamayo@usach.cl.
Abstract:
In this study, an antibacterial, but not cytotoxic nanomaterial based on polyethylene and copper nanoparticles was prepared by in situ polymerization. PE-CuNps nanocomposites against Escherichia coli, completely suppressed the number of live bacteria after 12 h incubation compared to neat PE. TEM images showed that nanocomposites damage the plasma membrane of the bacteria, revealing a bacteriolytic effect. Toxic effects of copper nanoparticles on viability of neuroblastoma line cell also was evaluated, revealing a non cytotoxic effect for the doses used, showing that this nanocomposite is a ideal material for medical devices.
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