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Updated: Apr 17, 2026

A Murine Model of Irreversible and Reversible Unilateral Ureteric Obstruction
Published on: December 20, 2014
Ureteral obstruction following partial nephrectomy: can it be caused by fibrin glue?
Timothy D Lyon1, Katherine M Theisen, Kevin J Rycyna
1University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Abstract:
Fibrin sealants are widely used during partial nephrectomy, however reports regarding the potential complications associated with their use are limited. We present the case of a 67-year-old male who developed delayed ureteral obstruction without hydronephrosis following partial nephrectomy in a solitary kidney. We hypothesize that the obstruction and absence of hydronephrosis were caused by extrinsic compression and subsequent inflammation due to the fibrin glue. Our report underscores the importance of a high index of suspicion for obstruction when acute kidney injury occurs following partial nephrectomy when fibrin glue is used, even in the absence of collecting system dilatation.
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