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Triple helix conformation-specific blinking of Cy3 in DNA
Kiyohiko Kawai1, Atsushi Maruyama
1The Institute of Scientific and Industrial Research, Osaka University, Mihogaoka 8-1, Ibaraki, Osaka 5670047, Japan. kiyohiko@sanken.osaka-u.ac.jp.
Chemical Communications (Cambridge, England)
|February 21, 2015
Abstract:
We report that Cy3 undergoes triple helix conformation-specific blinking in DNA. Blinking patterns were affected by the stabilization of the Hoogsteen base-pair, suggesting that not only the presence but also the fluctuating behaviour of the triple helix can be monitored by the changes in the Cy3 blinking patterns.
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