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Updated: Apr 17, 2026
09:58
Metal-free Synthesis of Ynones from Acyl Chlorides and Potassium Alkynyltrifluoroborate Salts
Published on: February 24, 2015
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Gold-acetonyl complexes: from side-products to valuable synthons.
Danila Gasperini1, Alba Collado, Adrián Goméz-Suárez
1EaStCHEM, School of Chemistry, University of St. Andrews, Purdie Building, North Haugh, St. Andrews, Fife, KY16 9ST (UK).
Chemistry (Weinheim an Der Bergstrasse, Germany)
|February 24, 2015
Summary
Researchers developed a new method to create gold acetonyl complexes using N-heterocyclic carbene ligands. These compounds are versatile building blocks and effective precatalysts for gold-catalyzed reactions.
Area of Science:
- Organometallic Chemistry
- Catalysis
- Synthetic Chemistry
Background:
- N-heterocyclic carbene (NHC) ligands are crucial in organometallic chemistry.
- Gold complexes are widely used in catalysis.
Purpose of the Study:
- To develop a novel synthetic strategy for gold acetonyl complexes.
- To explore the utility of these complexes as synthons and precatalysts.
Main Methods:
- A new synthetic route was established, utilizing a decomposition product from [Au(IPr)(Cl)] synthesis.
- A library of gold acetonyl complexes with various NHC ligands was prepared.
Main Results:
- Successful synthesis of gold acetonyl complexes, e.g., [Au(IPr)(CH2 COCH3)].
- Demonstrated utility of these complexes as versatile synthons for organogold compounds.
- Established their efficacy as precatalysts in gold(I)-catalyzed reactions.
Conclusions:
- The new synthetic strategy provides access to valuable gold acetonyl complexes.
- These complexes serve as important intermediates and precatalysts in gold chemistry.
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